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SACS Polyclonal Antibody, 20ul sgRNA Oligos Additional splice variation has been

SKU: 62730849286

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SACS Polyclonal Antibody, 20ul sgRNA Oligos Additional splice variation has beenThis gene encodes the sacsin protein, which includes a UbL domain at the N terminus, a DnaJ domain, and a HEPN domain at the C terminus. The gene is highly expressed in the central nervous system, also found in skin, skeletal muscles and at low levels in the pancreas. This gene includes a very large exon spanning more than 12. 8 kb. Mutations in this gene result in autosomal recessive spastic ataxia of Charlevoix Saguenay (ARSACS), a neurodegenerative

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Description

Additional splice variation has been identified but the full-length nature of these transcripts has not been determined

In contrast to IL-10

This gene encodes an integrin alpha chain and is expressed at high levels in chondrocytes

The precise function of this gene is unknown

The deduced sequence of the hypothetical protein of 132 aa does not share any similarity with that of functional CGB subunits (PMID:8954017)

SACS Polyclonal Antibody, 20ul sgRNA Oligos Additional splice variation has beenThis gene encodes the sacsin protein, which includes a UbL domain at the N terminus, a DnaJ domain, and a HEPN domain at the C terminus. The gene is highly expressed in the central nervous system, also found in skin, skeletal muscles and at low levels in the pancreas. This gene includes a very large exon spanning more than 12. 8 kb. Mutations in this gene result in autosomal recessive spastic ataxia of Charlevoix Saguenay (ARSACS), a neurodegenerative

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