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DIRC2 Polyclonal Antibody, 20ul Mechanical Pipette cyclin G2 contains a C-terminal

SKU: 63053661283

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DIRC2 Polyclonal Antibody, 20ul Mechanical Pipette cyclin G2 contains a C-terminalThis gene encodes a membrane bound protein from the major facilitator superfamily of transporters. Disruption of this gene by translocation has been associated with haplo insufficiency and renal cell carcinomas. Alternatively spliced transcript variants have been described, but their biological validity has not yet been determined.

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Description

cyclin G2 contains a C-terminal PEST protein destabilization motif

which function in cell migration

a dimerization domain near its N-terminus and an acidic N-terminus

thus| it functions as a regulator of a wide variety of downstream proteins| including tumor suppressor proteins p53 and BRCA1| checkpoint kinase CHK2| checkpoint proteins RAD17 and RAD9| and DNA repair protein NBS1

participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B

DIRC2 Polyclonal Antibody, 20ul Mechanical Pipette cyclin G2 contains a C-terminalThis gene encodes a membrane bound protein from the major facilitator superfamily of transporters. Disruption of this gene by translocation has been associated with haplo insufficiency and renal cell carcinomas. Alternatively spliced transcript variants have been described, but their biological validity has not yet been determined.

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