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LATS1/2(Phospho Thr1079/1041) Polyclonal Antibody, 20ul Centrifuges this mRNA is expressed only

SKU: 63680179133

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LATS1/2(Phospho Thr1079/1041) Polyclonal Antibody, 20ul Centrifuges this mRNA is expressed onlyThe protein encoded by this gene is a putative serine threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is phosphorylated in a cell cycle dependent manner, with late prophase phosphorylation remaining through metaphase. The N terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity, indicating a role as a negative

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Description

this mRNA is expressed only in testis

the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription

which interacts with histone deacetylase

The protein encoded by a similiar gene in mice was shown to bind to SH3 domains of protein-tyrosine kinases

Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy

LATS1/2(Phospho Thr1079/1041) Polyclonal Antibody, 20ul Centrifuges this mRNA is expressed onlyThe protein encoded by this gene is a putative serine threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is phosphorylated in a cell cycle dependent manner, with late prophase phosphorylation remaining through metaphase. The N terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity, indicating a role as a negative

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