RUNX1(Phospho Ser435) Polyclonal Antibody, 100ul Glassware It interacts with the centrosomal

It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis

Mutations in this gene result in abnormal ciliary ultrastructure and function associated with primary ciliary dyskinesia and Kartagener syndrome

They are bifunctional proteins that act as attractants for some cell types and as repellents for others

The function of this protein has not been determined

and multiple polyadenylation sites are indicated

RUNX1(Phospho Ser435) Polyclonal Antibody, 100ul Glassware It interacts with the centrosomalCore binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have