SQSTM1/p62 Rabbit Polyclonal Antibody, 100ul Peptide Library ALK/KIF5B (chromosome 10)

ALK/KIF5B (chromosome 10)

RCC1 (regulator of chromatin condensation 1) is the only known RanGEF

tissue specificity:Found in virtually all analyzed tumor cell lines including B- and T-lymphomas

This gene encodes an NADPH sensor protein that preferentially binds to NADPH

is quite deadly and the few who survive past one year suffer from permanent neurologic defects

SQSTM1/p62 Rabbit Polyclonal Antibody, 100ul Peptide Library ALK/KIF5B (chromosome 10)This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa B (NF kB) signaling pathway. The protein functions as a scaffolding adaptor protein in concert with TNF receptor associated factor 6 to mediate activation of NF kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in