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T2R40 Polyclonal Antibody, 20ul RNA Tools TAK1 activates the NF-κB pathway

SKU: 65399446111

4.1
EUR97.20 EUR120.20

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T2R40 Polyclonal Antibody, 20ul RNA Tools TAK1 activates the NF-κB pathwayGustducin coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium regulated cation channel TRPM5.,miscellaneous: Several bitter taste receptors are expressed in a single taste receptor cell.,Belongs to the G protein coupled receptor T2R family.,tissue specificity: Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin

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Description

TAK1 activates the NF-κB pathway by interacting with TRAF6 and phosphorylating the NF-κB inducing kinase (NIK)

An important paralog of this gene is RASL10A

a cell death regulator

while transcript variants initiating downstream of the interspersed NNAT gene (GeneID: 4826) are expressed from the paternal allele

This gene has three pseudogenes located on chromosomes 4

T2R40 Polyclonal Antibody, 20ul RNA Tools TAK1 activates the NF-κB pathwayGustducin coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium regulated cation channel TRPM5.,miscellaneous: Several bitter taste receptors are expressed in a single taste receptor cell.,Belongs to the G protein coupled receptor T2R family.,tissue specificity: Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin

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