DEF1 Polyclonal Antibody, 100ul Drug Development and Evaluation Also component of the mSin3A

Also component of the mSin3A complex which acts to repress transcription by deacetylation of nucleosomal histones

also named as MLL3P and CT2

Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter

and the T-cell receptor alpha/beta and gamma/delta heterodimers

invasion and metastasis of cancer cells

DEF1 Polyclonal Antibody, 100ul Drug Development and Evaluation Also component of the mSin3ADefensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1,