AN32D Polyclonal Antibody, 50ul Endonucleases & Exonucleases Multiple alternatively spliced transcript variants

Multiple alternatively spliced transcript variants encoding different isoforms have been found for GPSM1

and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters

It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation

Overexpressed in some cancer cells

and appear to regulate cytoskeletal organization

AN32D Polyclonal Antibody, 50ul Endonucleases & Exonucleases Multiple alternatively spliced transcript variantsPhosphoprotein 32 (PP32) is a tumor suppressor that can inhibit several types of cancers, including prostate and breast cancers. The protein encoded by this gene is one of at least two proteins that are similar in amino acid sequence to PP32 and are part of the same acidic nuclear phosphoprotein gene family. However, unlike PP32, the encoded protein is tumorigenic. The tumor suppressor function of PP32 has been localized to a 25 amino acid region that