Nibrin Polyclonal Antibody, 50ul[BT-AP06020] Recombinant Protein Expression Following activation

Following activation

This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen

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suggesting that this kinase may serve as an intermediate in the response to cellular stress

This protein may function in vesicle trafficking| membrane fusion| protein complex assembly and cell motility

Nibrin Polyclonal Antibody, 50ul[BT-AP06020] Recombinant Protein Expression Following activationMutations in NBN are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. Nibrin is a member of the MRE11 RAD50 double strand break repair complex which consists of 5 proteins. NBN product is thought to be involved in DNA double strand break repair and DNA damage induced checkpoint activation.