IκB-alpha(phospho Ser32/S36) Polyclonal Antibody, 20ul Adeno-associated Virus Packaging tissue specificity:Predominantly expressed in the

tissue specificity:Predominantly expressed in the lung and heart

which is required for ubiquitin-mediated degradation of cell cycle G1 regulators

Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability

This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis

it may function in fertility

IκB-alpha(phospho Ser32/S36) Polyclonal Antibody, 20ul Adeno-associated Virus Packaging tissue specificity:Predominantly expressed in theThis gene encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell