Raf-1(Phospho Ser642) Polyclonal Antibody, 20ul Organelle Studies Tumor necrosis factor ligand superfamily

Tumor necrosis factor ligand superfamily member 13B encoded by TNFSF13B is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family

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This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes| platelet dense granules| and lysosomes

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In mice| expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis

Raf-1(Phospho Ser642) Polyclonal Antibody, 20ul Organelle Studies Tumor necrosis factor ligand superfamilyThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.