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NFκB-p52 (Cleaved-A454) Rabbit Polyclonal Antibody, 100ul Human Genome Knockout Libraries Translocation t(3

SKU: 6708719990

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NFκB-p52 (Cleaved-A454) Rabbit Polyclonal Antibody, 100ul Human Genome Knockout Libraries Translocation t(3disease: A chromosomal aberration involving NFKB2 is found in a case of B cell non Hodgkin lymphoma (B NHL). Translocation t(10; 14)(q24; q32) with IGHA1. The resulting oncogene is also called Lyt 10C alpha variant. disease: A chromosomal aberration involving NFKB2 is found in a cutaneous T cell leukemia (C TCL) cell line. This rearrangement produces the p80HT gene which encodes for a truncated 80 kDa protein (p80HT). disease: In B cell leukemia (B

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Description

Translocation t(3

The products of target genes it activates are required for differentitation and mitogenesis

The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system

Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported| with the most common allele| Ile654/Ile655| shown here

Typing for these polymorphisms is routinely done for bone marrow and kidney trans

NFκB-p52 (Cleaved-A454) Rabbit Polyclonal Antibody, 100ul Human Genome Knockout Libraries Translocation t(3disease: A chromosomal aberration involving NFKB2 is found in a case of B cell non Hodgkin lymphoma (B NHL). Translocation t(10; 14)(q24; q32) with IGHA1. The resulting oncogene is also called Lyt 10C alpha variant. disease: A chromosomal aberration involving NFKB2 is found in a cutaneous T cell leukemia (C TCL) cell line. This rearrangement produces the p80HT gene which encodes for a truncated 80 kDa protein (p80HT). disease: In B cell leukemia (B

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