FOLR3 Polyclonal Antibody, 100ul Liquid Handling This gene and the WNT6

This gene and the WNT6 gene are clustered in the chromosome 2q35 region

The ATP binding cassette subfamily F member 1 encoded by ABCF1 is a member of the superfamily of ATP-binding cassette (ABC) transporters

As there is also a gene encoding a mitochondrial form of this enzyme

Contributes to invasiveness in malignant prostate cancer

including hereditary cancers such as Li-Fraumeni syndrome

FOLR3 Polyclonal Antibody, 100ul Liquid Handling This gene and the WNT6This gene encodes a member of the folate receptor (FOLR) family of proteins, which have a high affinity for folic acid and for several reduced folic acid derivatives, and mediate delivery of 5 methyltetrahydrofolate to the interior of cells. Expression of this gene may be elevated in ovarian and primary peritoneal carcinoma. This gene is present in a gene cluster on chromosome 11. Alternative splicing results in multiple transcript variants.