PRS54 Rabbit Polyclonal Antibody, 20ul sgRNA Oligos SIAH2 encodes E3 ubiquitin-protein ligase

SIAH2 encodes E3 ubiquitin-protein ligase SIAH2 that is a member of the seven in absentia homolog (SIAH) family

but no cytoplasmic death domain

Torsin-1A-interacting protein 1 localizes to the inner nuclear membrane and may be involved in maintaining the attachment of the nuclear membrane to the nuclear lamina during cell division

Ligand binding activates intracellular signaling cascades and the induction of cellular responses including proliferation

with this abnormal accumulation being specific to alpha-synucleinopathy lesions

PRS54 Rabbit Polyclonal Antibody, 20ul sgRNA Oligos SIAH2 encodes E3 ubiquitin-protein ligaseThis gene encodes a putative serine type endopeptidase containing the peptidase S1 domain. Alternative splicing of this gene results in multiple transcript variants.