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IKK gamma Polyclonal Antibody, 50ul[BT-AP02164] Peptide Library Alternatively spliced transcript variants have

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IKK gamma Polyclonal Antibody, 50ul[BT-AP02164] Peptide Library Alternatively spliced transcript variants haveThis gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex which activates NF kappaB resulting in activation of genes involved in inflammation immunity cell survival and other pathways. Mutations in this gene result in incontinentia pigmenti hypohidrotic ectodermal dysplasia and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.

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Description

Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined

and to a lesser extent in heart

Alternate splicing of this gene generates several transcript variants encoding different isoforms

Inositol polyphosphate multikinase has 3-kinase

Both calcium/calmodulin and protein phosphorylation mechanisms control its activity

IKK gamma Polyclonal Antibody, 50ul[BT-AP02164] Peptide Library Alternatively spliced transcript variants haveThis gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex which activates NF kappaB resulting in activation of genes involved in inflammation immunity cell survival and other pathways. Mutations in this gene result in incontinentia pigmenti hypohidrotic ectodermal dysplasia and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.

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