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Akt1 Polyclonal Antibody, 100ul[BT-AP00346] Cell Culture The encoded protein mediates the

SKU: 70063822307

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Akt1 Polyclonal Antibody, 100ul[BT-AP00346] Cell Culture The encoded protein mediates theThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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Description

The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel| ENaC

The encoded protein is a member of the BCL-2 family of cell death regulators

Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells

and is a member of a small gene family

XRN2 encodes a 5'-3' exonuclease that promotes transcription termination at cotranscriptional cleavage sites

Akt1 Polyclonal Antibody, 100ul[BT-AP00346] Cell Culture The encoded protein mediates theThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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