DAB2 Rabbit Polyclonal Antibody, 100ul Protein Post-translational Modification Gene Ontology (GO) annotations related

Gene Ontology (GO) annotations related to RABEP2 include GTPase activator activity and growth factor activity

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gastrointestinal dismay and skin rash

It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs)

epidermal keratinocytes

DAB2 Rabbit Polyclonal Antibody, 100ul Protein Post-translational Modification Gene Ontology (GO) annotations relatedThis gene encodes a mitogen responsive phosphoprotein. It is expressed in normal ovarian epithelial cells but is down regulated or absent from ovarian carcinoma cell lines suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2 an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras) via its C terminal proline rich sequences and may thus modulate growth factor Ras