Smad3 Polyclonal Antibody, 20ul[BT-AP08392] Oligo Pool Mutations in NR3C are associated

Mutations in NR3C are associated with generalized glucocorticoid resistance

SPI1 encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development

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PMEPA1 encodes a transmembrane protein that contains a Smad interacting motif (SIM)

SERPINF1 (serpin family F member 1) encodes a member of the serpin family that does not display the serine protease inhibitory activity shown by many of the other serpin proteins

Smad3 Polyclonal Antibody, 20ul[BT-AP08392] Oligo Pool Mutations in NR3C are associatedThe protein encoded by SMAD3 belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor beta and is thought to play a role in the regulation of