Mouse Dickkopf-related Protein 1, DKK1 ELISA Kit, 96T Human Genome Knockout Libraries It is sensitive to brefeldin
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Mouse Dickkopf-related Protein 1, DKK1 ELISA Kit, 96T Human Genome Knockout Libraries It is sensitive to brefeldinAntagonizes canonical Wnt signaling by inhibiting LRP5 6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5 6 (PubMed: 18524778). Inhibits the pro apoptotic function of KREMEN1 in a Wnt independent manner, and has anti apoptotic activity (PubMed: 26206087). Plays a role in limb development; attenuates Wnt signaling in the developing limb to allow normal limb patterning
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