Rb Polyclonal Antibody, 100ul[BT-AP07689] Diagnostic Probes & Oligos Mitofusin-2 is involved in the

Mitofusin-2 is involved in the regulation of vascular smooth muscle cell proliferation

which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies

CABC1 expression is induced both in response to DNA damage and by the tumor suppressor p53

This gene encodes both smooth muscle and nonmuscle isoforms

particularly in cells of the myeloid and B-lymphoid lineages

Rb Polyclonal Antibody, 100ul[BT-AP07689] Diagnostic Probes & Oligos Mitofusin-2 is involved in theRB transcriptional corepressor 1 encoded by RB1 is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.