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IKK gamma(Phospho Ser376) Polyclonal Antibody, 20ul In vitro Transcription autoimmune diseases and prostate cancer

SKU: 71095307535

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DKK97.20 DKK130.20

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IKK gamma(Phospho Ser376) Polyclonal Antibody, 20ul In vitro Transcription autoimmune diseases and prostate cancerThis gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex which activates NF kappaB resulting in activation of genes involved in inflammation immunity cell survival and other pathways. Mutations in this gene result in incontinentia pigmenti hypohidrotic ectodermal dysplasia and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.

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Description

autoimmune diseases and prostate cancer

Multiple transcript variants encoding different isoforms have been found for EIF2B4

Most of the variants are the result of gene recombinations between GYPA and GYPB

Demethylation of Lys residue generates formaldehyde and succinate

Deficiency of this enzyme activity results in the autosomal recessive disorder phenylketonuria

IKK gamma(Phospho Ser376) Polyclonal Antibody, 20ul In vitro Transcription autoimmune diseases and prostate cancerThis gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex which activates NF kappaB resulting in activation of genes involved in inflammation immunity cell survival and other pathways. Mutations in this gene result in incontinentia pigmenti hypohidrotic ectodermal dysplasia and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.

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