HLA-DM beta Polyclonal Antibody, 100ul Cell Culture Plates Class II AP endonucleases cleave

Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site

Contains 1 thioredoxin domain

bronchial and small airway lung epithelial cells

serves as the scaffold for assembly of the remainder of the transcription complex

The protein is involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction

HLA-DM beta Polyclonal Antibody, 100ul Cell Culture Plates Class II AP endonucleases cleaveHLA DMB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chain, both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II associated invariant chain peptide) molecule from the peptide binding site. Class II molecules are expressed in