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ACHA6 Polyclonal Antibody, 100ul Low retention tips Nucleoside transporters are required for

SKU: 715198502

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ACHA6 Polyclonal Antibody, 100ul Low retention tips Nucleoside transporters are required forThis gene encodes an alpha subunit of neuronal nicotinic acetylcholine receptors. These receptors consist of five subunits and function as ion channels involved in neurotransmission. The encoded protein is a subunit of neuronal nicotinic acetylcholine receptors that mediate dopaminergic neurotransmission and are activated by acetylcholine and exogenous nicotine. Alternatively spliced transcript variants have been observed for this gene. Single

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Description

Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways

the protein binds to iron-responsive elements (IREs)

The encoded protein| upon tyrosine phosphorylation| has been shown to recruit the Src homology 2 domain-containing protein-tyrosine phosphatases SHP1 and SHP2

This gene is also associated with translocations in patients with B-cell chronic lymphocytic leukemia

Members of the connecdenn family| such as DENND1B| function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2

ACHA6 Polyclonal Antibody, 100ul Low retention tips Nucleoside transporters are required forThis gene encodes an alpha subunit of neuronal nicotinic acetylcholine receptors. These receptors consist of five subunits and function as ion channels involved in neurotransmission. The encoded protein is a subunit of neuronal nicotinic acetylcholine receptors that mediate dopaminergic neurotransmission and are activated by acetylcholine and exogenous nicotine. Alternatively spliced transcript variants have been observed for this gene. Single

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