TOP1M Polyclonal Antibody, 20ul Cell Dissociation These serine proteases are collectively

These serine proteases are collectively termed granzymes and include 4 distinct gene products: granzyme A

Proteolytic cleavage leads to the activation of the receptor

Additional isoforms produced by alternative splicing seem to exist

Members of this family are important during development

This gene encodes a member of the Rab40 subfamily of Rab small GTP-binding proteins that contains a C-terminal suppressors of cytokine signaling box

TOP1M Polyclonal Antibody, 20ul Cell Dissociation These serine proteases are collectivelyThis gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.