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PDK2 Polyclonal Antibody, 100ul Nucleic Acid Isolation & Purification Members of the defensin family

SKU: 71879547803

4.2
PLN123.75 PLN169.75

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PDK2 Polyclonal Antibody, 100ul Nucleic Acid Isolation & Purification Members of the defensin familyPDK2 encodes a member of the pyruvate dehydrogenase kinase family. Pyruvate dehydrogenase kinase 2 phosphorylates pyruvate dehydrogenase, down regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of PDK2 may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for PDK2.

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Description

Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif

and expansion of the number of repeats to 45-66 increases the length of the polyglutamine string and is associated with spinocerebellar ataxia 17

Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activition or by arresting cell growth in G1 phase in a p53-dependent manner

The re-sealable bag ensures long-lasting use

Noonan syndrome and trisomy 12p

PDK2 Polyclonal Antibody, 100ul Nucleic Acid Isolation & Purification Members of the defensin familyPDK2 encodes a member of the pyruvate dehydrogenase kinase family. Pyruvate dehydrogenase kinase 2 phosphorylates pyruvate dehydrogenase, down regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of PDK2 may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for PDK2.

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