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Rock-1 Polyclonal Antibody, 100ul Microbial Genome Editing The product of KRT8 typically

SKU: 72010748442

4.2
SEK123.75 SEK146.75

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Rock-1 Polyclonal Antibody, 100ul Microbial Genome Editing The product of KRT8 typicallyThis gene encodes a protein serine threonine kinase that is activated when bound to the GTP bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP bound form and the active GTP bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response

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Description

The product of KRT8 typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells

The encoded protein may promote neurite outgrowth and adhesion via a homophilic mechanism

The functional domains of p53 family proteins include an N-terminal transactivation domain

Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy

where it may contribute to insulin resistance in glucose uptake

Rock-1 Polyclonal Antibody, 100ul Microbial Genome Editing The product of KRT8 typicallyThis gene encodes a protein serine threonine kinase that is activated when bound to the GTP bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP bound form and the active GTP bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response

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