PCP Polyclonal Antibody, 20ul[BT-AP12850] Centrifugal Filter Mutations in this gene result

Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy

1-10μl measurements

Serine/threonine-protein kinase mTOR acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex

This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways

The cell division cycle-associated protein 2 may also play a role in cancer progression

PCP Polyclonal Antibody, 20ul[BT-AP12850] Centrifugal Filter Mutations in this gene resultThis gene encodes a member of the peptidase S28 family of serine exopeptidases. The encoded preproprotein is proteolytically processed to generate the mature lysosomal prolylcarboxypeptidase. This enzyme cleaves C terminal amino acids linked to proline in peptides such as angiotension II, III and des Arg9 bradykinin. The cleavage occurs at acidic pH, but the enzyme activity is retained with some substrates at neutral pH. This enzyme has been shown to