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Oct-3/4 Polyclonal Antibody, 100ul[BT-AP06332] Capsule Filter This gene product is the

SKU: 72507314614

4.5
SEK141.00 SEK162.00

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Oct-3/4 Polyclonal Antibody, 100ul[BT-AP06332] Capsule Filter This gene product is thePOU5F1 (POU class 5 homeobox 1) encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of POU5F1 in adult tissues is associated with tumorigenesis. POU5F1 can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non AUG

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Description

This gene product is the human homolog of mouse Tbx2

where they participate in a wide range of physiologic responses

Mutations in this gene cause familial hypocalciuric hypercalcemia

and autosomal recessive acute recurrent myoglobinuria (ARARM)

alpha 1 by only one amino acid

Oct-3/4 Polyclonal Antibody, 100ul[BT-AP06332] Capsule Filter This gene product is thePOU5F1 (POU class 5 homeobox 1) encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of POU5F1 in adult tissues is associated with tumorigenesis. POU5F1 can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non AUG

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