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CD63 Polyclonal Antibody, 50ul[BT-AP01867] Peptide Synthesis The active| hypophosphorylated form of

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CD63 Polyclonal Antibody, 50ul[BT-AP01867] Peptide Synthesis The active| hypophosphorylated form ofCLCNKA is a member of the CLC family of voltage gated chloride channels. The encoded protein (chloride voltage gated channel Ka) is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel. It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear. The gene is highly similar to CLCNKB, which is located 10 kb downstream from this gene. Multiple

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Description

The active| hypophosphorylated form of the protein binds transcription factor E2F1

several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways

The N-terminus is composed of the phosphotyrosine binding (PTB) domain

A highly similar protein in mouse has both ferrireductase and cupric reductase activity

Mutations in this gene have been associated with hereditary hemochromatosis type III

CD63 Polyclonal Antibody, 50ul[BT-AP01867] Peptide Synthesis The active| hypophosphorylated form ofCLCNKA is a member of the CLC family of voltage gated chloride channels. The encoded protein (chloride voltage gated channel Ka) is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel. It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear. The gene is highly similar to CLCNKB, which is located 10 kb downstream from this gene. Multiple

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