PYK2 Polyclonal Antibody, 50ul[BT-AP07520] Microplate Mixer Mutations in this gene have

Mutations in this gene have been associated with Chronic Atrial and Intestinal Dysrhythmia (CAID) syndrome

also named as C21orf108

The functions of the different isoforms are not known

Some Bartter-like syndromes result from defects in this gene

Multiple alternatively spliced variants| encoding the same protein| have been identified

PYK2 Polyclonal Antibody, 50ul[BT-AP07520] Microplate Mixer Mutations in this gene havePTK2B encodes a cytoplasmic protein tyrosine kinase which is involved in calcium induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and