IRS-1(Phospho-Ser612) Rabbit Polyclonal Antibody, 20ul CellSafe™ an intronic CTG repeat normally

an intronic CTG repeat normally numbering 10-37 repeat units can expand to >50 repeat units and cause Fuchs endothelial corneal dystrophy

Microdeletions in this gene are associated with contiguous ABCD1/DXS1375E deletion syndrome (CADDS)

A long isoform of the protein has an N-terminal domain that is homologous to the extracellular part of frizzled receptors

in the initiation of translation

The protein encoded by this gene is a calcium-activated nonselective ion channel that mediates transport of monovalent cations across membranes| thereby depolarizing the membrane

IRS-1(Phospho-Ser612) Rabbit Polyclonal Antibody, 20ul CellSafe™ an intronic CTG repeat normallyThis gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.