Sgo1 Polyclonal Antibody, 50ul Custom DNA Oligos This gene encodes the cytosolic

This gene encodes the cytosolic isozyme

Tyrosine protein kinases are important regulators of intracellular signal transduction pathways| mediating cellular proliferation| survival| and development

disease:A chromosomal rearrangement involving CTNNB1 may be a cause of salivary gland pleiomorphic adenomas (PA)

Defects in this gene cause autosomal dominant spinocerebellar ataxia 12 (SCA12)

Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism

Sgo1 Polyclonal Antibody, 50ul Custom DNA Oligos This gene encodes the cytosolicShugoshin like 1 encoded by SGOL1 is a member of the shugoshin family of proteins. This protein is thought to protect centromeric cohesin from cleavage during mitotic prophase by preventing phosphorylation of a cohesin subunit. Reduced expression of this gene leads to the premature loss of centromeric cohesion, mis segregation of sister chromatids, and mitotic arrest. Evidence suggests that this protein also protects a small subset of cohesin found