GRP78/Bip Monoclonal Antibody(10C9), 100ul Low retention tips Deacetylation by SIRT1 is NAD-dependent

Deacetylation by SIRT1 is NAD-dependent and stimulates transcriptional activity

This gene encodes the human homolog of yeast class C Vps18 protein

May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53

and in a head-to-head orientation with the gene for the mitochondrial ribosomal protein L34

and can activate the nuclear factor-kappaB

GRP78/Bip Monoclonal Antibody(10C9), 100ul Low retention tips Deacetylation by SIRT1 is NAD-dependentThe protein encoded by this gene is a member of the heat shock protein 70 (HSP70) family. It is localized in the lumen of the endoplasmic reticulum (ER), and is involved in the folding and assembly of proteins in the ER. As this protein interacts with many ER proteins, it may play a key role in monitoring protein transport through the cell.