Glycerate Kinase Polyclonal Antibody, 100ul Immune Cell Analysis This gene is part of

This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor that may regulate gene expression

|PTM:Polyubiquitination seems to allow p105 processing

such as colon

Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype

they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor

Glycerate Kinase Polyclonal Antibody, 100ul Immune Cell Analysis This gene is part ofThis locus encodes a member of the glycerate kinase type 2 family. The encoded enzyme catalyzes the phosphorylation of (R) glycerate and may be involved in serine degradation and fructose metabolism. Decreased activity of the encoded enzyme may be associated with the disease D glyceric aciduria. Alternatively spliced transcript variants have been described.