eIF4G(Phospho-Ser1108) Rabbit Polyclonal Antibody, 100ul Lysosome Repressor that binds to DNA

Repressor that binds to DNA sequences containing a bipartite element consisting of a direct repeat of the sequence 5'-AAAGTTT-3' separated by 2-9 nucleotides

regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth

Drosophila

Mutations in this gene are the cause of brachydactyly type A1

Mutations in ZNF592 have been associated with autosomal recessive spinocerebellar ataxia

eIF4G(Phospho-Ser1108) Rabbit Polyclonal Antibody, 100ul Lysosome Repressor that binds to DNAThe protein encoded by this gene is a component of the multi subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome which is a rate limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP dependent unwinding of 5' terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains