SMRD1 Polyclonal Antibody, 50ul Pathway and Network Analysis The encoded protein negatively regulates

The encoded protein negatively regulates wingless/integrated signaling through interaction with the post synaptic density protein/ Drosophila disc large tumor suppressor/ zonula occludens-1 protein domain of Dishevelled| a scaffolding protein required for the stabilization of the transcriptional co-activator beta-catenin

this gene appears to be involved in regulation of cell proliferation

and a serine/proline-rich domain in between the doublecortin and the protein kinase domains

This protein localizes predominantly to the perinuclear region

The gene product is an integral membrane protein that is thought to function in cell-cell recognition and adhesion

SMRD1 Polyclonal Antibody, 50ul Pathway and Network Analysis The encoded protein negatively regulatesThe protein encoded by this gene is a member of the SWI SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP dependent chromatin remodeling complex SNF SWI and has sequence similarity to the yeast Swp73 protein. Two transcript variants encoding different isoforms