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Rb Polyclonal Antibody, 100ul[BT-AP07685] Monoclonal Antibody Preparation This magnesium-binding protein forms homodimers

SKU: 7666208045

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Rb Polyclonal Antibody, 100ul[BT-AP07685] Monoclonal Antibody Preparation This magnesium-binding protein forms homodimersRB transcriptional corepressor 1 encoded by RB1 is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

This magnesium-binding protein forms homodimers and is located in the cytoplasm

including breast and ovarian tumors

It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells

Diseases associated with ZMYM4 include non-syndromic x-linked intellectual disability

but also come in a convenient plastic rack packing

Rb Polyclonal Antibody, 100ul[BT-AP07685] Monoclonal Antibody Preparation This magnesium-binding protein forms homodimersRB transcriptional corepressor 1 encoded by RB1 is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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