RASF5 Rabbit Polyclonal Antibody, 20ul Micro Centrifuge Tubes Mutations in this gene have

Mutations in this gene have been associated with Holt-Oram syndrome

This protein participates in DNA replication and may play a role in modulating chromatin formation and contribute to the regulation of cell proliferation

Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC

Transcriptional activation of CCNG1 can be induced by tumor protein p53

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RASF5 Rabbit Polyclonal Antibody, 20ul Micro Centrifuge Tubes Mutations in this gene haveThis gene is a member of the Ras association domain family. It functions as a tumor suppressor and is inactivated in a variety of cancers. The encoded protein localizes to centrosomes and microtubules and associates with the GTP activated forms of Ras Rap1 and several other Ras like small GTPases. The protein regulates lymphocyte adhesion and suppresses cell growth in response to activated Rap1 or Ras. Multiple transcript variants encoding different