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GRIK3 Rabbit Polyclonal Antibody, 50ul High Speed Micro-Centrifuges The p70/p80 autoantigen is a

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SEK162.00 SEK191.00

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GRIK3 Rabbit Polyclonal Antibody, 50ul High Speed Micro-Centrifuges The p70/p80 autoantigen is aGlutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors which are composed of four subunits and function as ligand activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A

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Description

The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa

Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene

thereby maintaining these factors in an inactive state

this protein can be recruited by TNFRSF6/Fas-receptor

Mutations in MT-CO1 have been associated with Leber's hereditary optic neuropathy (LHON)

GRIK3 Rabbit Polyclonal Antibody, 50ul High Speed Micro-Centrifuges The p70/p80 autoantigen is aGlutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors which are composed of four subunits and function as ligand activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A

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