Rb(Phospho Ser788) Polyclonal Antibody, 50ul Liquid Handling ＆Storage An additional transcript variant has

An additional transcript variant has been identified

also known as F-actin bundling domain

The protein encoded by TNFRSF17 (TNF receptor superfamily member 17) is a member of the TNF-receptor superfamily

neither of which is effective on its own

Several transcript variants encoding different isoforms have been found for this gene

Rb(Phospho Ser788) Polyclonal Antibody, 50ul Liquid Handling ＆Storage An additional transcript variant hasThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.