ENOF1 Polyclonal Antibody, 20ul Liquid Handling the ubiquitin ligase activity being

the ubiquitin ligase activity being mediated by RBX1

Four alternatively spliced transcript variants of this gene encoding d

It can regulate cell motility by targeting paxillin ubiquitination and altering the distribution and localization of paxillin in cytoplasm and cell focal adhesions

Targeted disruption of this gene in mice affects embryonic viability

1 superfamily cytoskeleton-associated proteins

ENOF1 Polyclonal Antibody, 20ul Liquid Handling the ubiquitin ligase activity beingThis gene was originally identified as a naturally occurring antisense transcript to the human thymidylate synthase gene. Alternate splice variants have been described, one of which (named rTSalpha) represents an alternate 3'UTR that is complementary to the 3'UTR and terminal intron of the thymidylate synthase (TS) RNA and down regulates TS expression. Other transcript variants (rTSbeta and rTSgamma) do not overlap the TS locus. The function of this