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IGFBP1 Polyclonal Antibody, 20ul[BT-AP04386] Protein Post-translational Modification for the liver- and erythocyte-specific

SKU: 78447648226

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IGFBP1 Polyclonal Antibody, 20ul[BT-AP04386] Protein Post-translational Modification for the liver- and erythocyte-specificIGFBP1 is a member of the insulin like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type I domain. The protein binds both insulin like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half life of the IGFs and alters their interaction with cell surface receptors.

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Description

for the liver- and erythocyte-specific isoforms

the encoded protein may increase the viability of certain cell types through modulation of p53 activity

the other in G2

A translocation of POU4F1 is associated with some adult acute myeloid leukemias

Several transcript variants encoding different isoforms have been found for this gene

IGFBP1 Polyclonal Antibody, 20ul[BT-AP04386] Protein Post-translational Modification for the liver- and erythocyte-specificIGFBP1 is a member of the insulin like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type I domain. The protein binds both insulin like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half life of the IGFs and alters their interaction with cell surface receptors.

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