Cdk9(Phospho Thr186) Polyclonal Antibody, 100ul Cryopreservation Mutations in ELAC2 result in

Mutations in ELAC2 result in an increased risk of prostate cancer

such as SFRS1 and SFRS2 on serine residues

This family is comprised of nuclear phosphoproteins that modulate transcription in a promoter context-dependent manner

Mediator complex subunit 23 encoded by MED23 is a subunit of the CRSP (cofactor required for SP1 activation) complex

and its expression is upregulated in several kinds of carcinomas

Cdk9(Phospho Thr186) Polyclonal Antibody, 100ul Cryopreservation Mutations in ELAC2 result inThe protein encoded by this gene is a member of the cyclin dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK P TEFb, which is an elongation factor for RNA polymerase II directed transcription and functions by phosphorylating the C terminal domain