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Hic-5 Polyclonal Antibody, 100ul[BT-AP03963] Syringe Filter This gene encodes a stefin

SKU: 79405611463

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Hic-5 Polyclonal Antibody, 100ul[BT-AP03963] Syringe Filter This gene encodes a stefinTGFB1I1 (transforming growth factor beta 1 induced transcript 1) encodes a coactivator of the androgen receptor, a transcription factor which is activated by androgen and has a key role in male sexual differentiation. The encoded protein is thought to regulate androgen receptor activity and may have a role to play in the treatment of prostate cancer. Multiple transcript variants encoding different isoforms have been found for TGFB1I1.

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Description

This gene encodes a stefin that functions as a cysteine protease inhibitor

endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane

This protein also belongs to a large family of ligand-inducible transcription factors that regulate gene expression by binding to specific DNA sequences within promoters of target genes

amplification and overexpression of CCND1

cofactor or changes in kinetic properties distinguishing it from other carbohydrate kinases

Hic-5 Polyclonal Antibody, 100ul[BT-AP03963] Syringe Filter This gene encodes a stefinTGFB1I1 (transforming growth factor beta 1 induced transcript 1) encodes a coactivator of the androgen receptor, a transcription factor which is activated by androgen and has a key role in male sexual differentiation. The encoded protein is thought to regulate androgen receptor activity and may have a role to play in the treatment of prostate cancer. Multiple transcript variants encoding different isoforms have been found for TGFB1I1.

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