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Girdin Polyclonal Antibody, 50ul Liquid Handling &Storage which may contribute to the

SKU: 7950732335

4.6
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Girdin Polyclonal Antibody, 50ul Liquid Handling &Storage which may contribute to theCCDC88A (coiled coil domain containing 88A) encodes a member of the Girdin family of coiled coil domain containing proteins. The encoded protein is an actin binding protein that is activated by the serine threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3 kinase (PI3K) dependent activation of Akt by growth factor receptor tyrosine kinases

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Description

which may contribute to the pathogenesis

Required for the polarization of forebrain neurons which endows axons and dendrites with distinct properties

inhibition of neuroblastoma cell differentiation

and overexpression of CA8 in osteosarcoma cells suggests an oncogenic role

mutations in this gene

Girdin Polyclonal Antibody, 50ul Liquid Handling &Storage which may contribute to theCCDC88A (coiled coil domain containing 88A) encodes a member of the Girdin family of coiled coil domain containing proteins. The encoded protein is an actin binding protein that is activated by the serine threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3 kinase (PI3K) dependent activation of Akt by growth factor receptor tyrosine kinases

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