PEF1 Rabbit Polyclonal Antibody, 100ul Serum elevated intracellular calcium levels induce

elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group

Its substrates include the oxysterols 25-hydroxycholesterol

Sterols inhibit the cleavage of the precursor

which are important in RNA binding and are known to be involved in RNA synthesis and metabolism

It is a mainly cytoplasmic protein that can translocate to the cell membrane after cell stimulation

PEF1 Rabbit Polyclonal Antibody, 100ul Serum elevated intracellular calcium levels induceThis gene encodes a calcium binding protein belonging to the penta EF hand protein family. The encoded protein has been shown to form a heterodimer with the programmed cell death 6 gene product and may modulate its function in Ca(2+) signaling. Alternative splicing results in multiple transcript variants and a pseudogene has been identified on chromosome 1.