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Oct-3/4 Polyclonal Antibody, 50ul[BT-AP06332] Multi-Layer Cell Culture System PTM:Phosphorylated in a cell-cycle-dependent manner

SKU: 80479399647

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Oct-3/4 Polyclonal Antibody, 50ul[BT-AP06332] Multi-Layer Cell Culture System PTM:Phosphorylated in a cell-cycle-dependent mannerPOU5F1 (POU class 5 homeobox 1) encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of POU5F1 in adult tissues is associated with tumorigenesis. POU5F1 can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non AUG

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Description

PTM:Phosphorylated in a cell-cycle-dependent manner (from the S phase until mitosis)

Lipase member I encoded by LIPI is a phospholipase that hydrolyzes phosphatidic acid to produce lysophosphatidic acid

thereby playing a key role in regulating the cellular redox environment

Mutations in this gene are associated with ectodermal dysplasia| and cleft lip/palate syndrome 3 (EEC3)

Defects in ARNTL have been linked to infertility

Oct-3/4 Polyclonal Antibody, 50ul[BT-AP06332] Multi-Layer Cell Culture System PTM:Phosphorylated in a cell-cycle-dependent mannerPOU5F1 (POU class 5 homeobox 1) encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of POU5F1 in adult tissues is associated with tumorigenesis. POU5F1 can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non AUG

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