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AZ1 Polyclonal Antibody, 100ul Reservoirs Autoantibodies against this protein have

SKU: 81371342397

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AZ1 Polyclonal Antibody, 100ul Reservoirs Autoantibodies against this protein haveThe protein encoded by OAZ1 belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamines. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis; thus, completing the auto regulatory circuit. OAZ1

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Description

Autoantibodies against this protein have been found in patients with cancer or graft versus host disease

Capacity:5/15mL × 28

The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins

The protein encoded by this gene functions as a transcriptional coactivator for nuclear hormone receptors

Tumor suppressor

AZ1 Polyclonal Antibody, 100ul Reservoirs Autoantibodies against this protein haveThe protein encoded by OAZ1 belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamines. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis; thus, completing the auto regulatory circuit. OAZ1

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