Mcl-1 Polyclonal Antibody, 50ul[BT-AP05274] Subcellular Fractions Binding of the ligand inhibits

Binding of the ligand inhibits cAMP accumulation

Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues

and is involved in calcium sequestration associated with muscular excitation and contraction

tissue specificity:Testis-specific

which is a conserved DNA-binding domain that has striking similarity to the site-specific DNA-binding domain (DBD) of Drosophila P element transposases

Mcl-1 Polyclonal Antibody, 50ul[BT-AP05274] Subcellular Fractions Binding of the ligand inhibitsMCL1 encodes an anti apoptotic protein, which is a member of the Bcl 2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death inducing.