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Rb(Phospho Thr821) Polyclonal Antibody, 20ul DNA Fragments The protein encoded by this

SKU: 82028813953

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SEK85.00 SEK128.00

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Rb(Phospho Thr821) Polyclonal Antibody, 20ul DNA Fragments The protein encoded by thisThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

The protein encoded by this gene is a peroxisomal flavoprotein that catalyzes the oxidative deamination of D-aspartate and N-methyl D-aspartate

The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains

This protein is involved in cell adhesion

coiled-coil region and arginine

Reduces all-trans-retinal and 9-cis retinal

Rb(Phospho Thr821) Polyclonal Antibody, 20ul DNA Fragments The protein encoded by thisThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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